Circulatory System Surgery Cardiology Anaesthesia
Conditions
Interventions
Group A
Group B
Sponsors
Faculty of Medicine Ain shams university
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? Age between 18-65 years old. ? Patients with preoperative mitral valve disease (isolated mitral stenosis, regurgitation or combined stenosis and regurgitation) with pulmonary hypertension (mean pulmonary arterial pressure > 40 mmHg) admitted to postoperative ICU after already performed elective mitral valve replacement surgery. ? Both genders. ? Left ventricular ejection fractions over 40%.
Exclusion criteria
Exclusion criteria: ? Patient undergoing emergency surgery. ? Redo surgeries. ? History of chronic obstructive pulmonary disease, severe renal disease, liver dysfunction, coagulopathy or thrombocytopenia. ? Patients with thromboembolic disease treated with anticoagulation therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| oHemodynamic parameters including: heart rate, systolic arterial pressure, diastolic arterial pressure, mean arterial pressure, central venous pressure, systolic pulmonary artery pressure, diastolic pulmonary artery pressure, mean pulmonary artery pressure, ejection fraction and fractional shortening. | — |
Secondary
| Measure | Time frame |
|---|---|
| o Arterial and central venous blood samples will be obtained during each assessment point and immediately analyzed and arterial oxygen tension/fraction of inspired oxygen (PaO2/FiO2) ratio will be calculated by standard formulas. | — |
Countries
Egypt
Contacts
Public ContactSherif Sultan
Professor at department of Anesthesia Intensive Care and Pain Management Faculty of Medicine Ain Shams University
Outcome results
None listed