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THE EFFECT OF SALINE FLUSH AFTER ROCURONIUM BOLUS ON THE PROPORTION OF PATIENTS WITH EXCELLENT INTUBATING CONDITIONS IN ADULT PATIENTS UNDERGOING ELECTIVE SURGERY AT AGA KHAN UNIVERSITY HOSPITAL NAIROBI

THE EFFECT OF SALINE FLUSH AFTER ROCURONIUM BOLUS ON THE PROPORTION OF PATIENTS WITH EXCELLENT INTUBATING CONDITIONS IN ADULT PATIENTS UNDERGOING ELECTIVE SURGERY AT AGA KHAN UNIVERSITY HOSPITAL NAIROBI

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202105778223198
Enrollment
62
Registered
2021-05-19
Start date
2018-11-10
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Rocuronium group

Sponsors

Aga Khan University Research Committee
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients between 18-65 years scheduled for non-emergent surgery under general anaesthesia requiring oral endotracheal intubation. Patients scheduled for surgery between 8 a.m. and 6 p.m. (This is the time when elective cases are scheduled in the study institution). Patients with ASA grade I to III. Patients whose anaesthetic technique included total intravenous anaesthesia (TIVA).

Exclusion criteria

Exclusion criteria: • Patients who declined to consent to participation in the study. • Patients known to have an allergy to rocuronium or any other of the study drugs. • Patients scheduled for emergency surgery. • Patients with ASA category IV to VI. • Patients known to have a difficult airway (from previous anaesthetic notes or history) or suspected to have a difficult airway using the modified LEMON criteria score (including a body mass index (BMI) above 35kg/m2) during the anaesthesia review. • Patients who had non-emergency surgery scheduled between 6 p.m. and 8 a.m. • Patients with heart failure or chronic liver disease and pregnant patients were excluded from the study.

Design outcomes

Primary

MeasureTime frame
To determine the effect of a 20ml saline flush after 0.6 milligrams per kilogram intravenous Rocuronium on the proportion of patients with excellent intubating conditions at one minute assessed by the Goldberg scale in adult patients undergoing elective surgery under general anaesthesia at AKUH-N.

Secondary

MeasureTime frame
To determine the relationship between intubating conditions and the twitch height at one minute following a saline flush with 0.6 milligrams per kilogram intravenous Rocuronium in patients having elective surgery under general anaesthesia with oral endotracheal intubation at AKUH-N.;To determine the effect of saline flush after 0.6 milligrams per kilogram intravenous Rocuronium on the onset time of Rocuronium as measured by the degree of twitch height depression in adult patients undergoing elective surgery under general anaesthesia at AKUH-N.

Countries

Kenya

Contacts

Public ContactRajpreet Bal

Fulltime Academic Faculty

rajpreet.bal@aku.edu+254738496298

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026