Granulocyte-Macrophage Colony-Stimulating Factor containing medium for Recurrent Pregnancy Loss Patients.

The use of culture medium supplemented with Granulocyte-Macrophage Colony-Stimulating Factor for Recurrent Pregnancy Loss Patients, A pilot study on 200 cases.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202105562059108

Enrollment

200

Registered

2021-05-17

Start date

2021-04-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fertility-female

Interventions

Embryo culture and transfer in GMCSF supplemented medium.

Embryo culture and transfer in medium not supplemented by GMCSF.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women aged 19 to 44 years and had a history recurrent miscarriage: loss of two or more consecutive pregnancies before 20 weeks. Those women should have a regular menstrual cycle of 21 to 35 days, treated per standard protocols.

Exclusion criteria

Exclusion criteria: Women aged over 44 or had an anatomic disorder of the uterus, chromosomal defects in the couple, medical conditions or genetic disorders prohibiting IVF/ICSI or interfering with the interpretation of results. ICSI cycles requiring pre-implantation genetic diagnosis.

Design outcomes

Primary

Measure	Time frame
Continued pregnancy	—

Secondary

Measure	Time frame
Clinical pregnancy	—

Countries

Egypt

Contacts

Public ContactEmad Fakhry

Adam International Hospital

emadfakhrylabib@gmail.com+201287508483

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026