MAMI-RCT Study

Randomized Controlled Trial to Compare the Effect of Corn-Soy Blend + Vegetable Oil and Fish Oil (CSB-VO-FO) With Corn-Soy Blend + Vegetable Oil Alone (CSB-VO) on the Immunological and Microbiota Patterns among Children Aged 9 to 24 months with Moderate Acute Malnutrition (MAM)

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202105499634368

Enrollment

Registered

2021-05-06

Start date

2018-07-02

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nutritional, Metabolic, Endocrine

Interventions

Corn Soy Blend and Vegetable Oil

Corn Soy Blend and Ultimate Omega Fish Oil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Resident and living within Kibera Slums in Nairobi for the duration of the study. Aged 9-24 months. With MAM, defined as mid-upper arm circumference (MUAC) of 11.5 to <12.5cm. Caregiver is able and willing to provide informed consent.

Exclusion criteria

Exclusion criteria: Severe acute malnutrition (SAM) WLZ37.5°C. Gross Congenital abnormalities

Design outcomes

Primary

Measure	Time frame
Incidence of infectious diseases among children with moderate acute malnutrition receiving either corn-soy blend with vegetable oil and fish oil or corn-soy blend with vegetable oil alone.;Effect of corn-soy blend with vegetable oil and fish oil compared to corn-soy blend with vegetable oil alone on level of expression of inflammatory markers in children with moderate acute malnutrition.;Effect of corn-soy blend with vegetable oil and fish oil compared to corn-soy blend with vegetable oil alone on the composition of fecal microbiota.	—

Measure

Time frame

Incidence of infectious diseases among children with moderate acute malnutrition receiving either corn-soy blend with vegetable oil and fish oil or corn-soy blend with vegetable oil alone.;Effect of corn-soy blend with vegetable oil and fish oil compared to corn-soy blend with vegetable oil alone on level of expression of inflammatory markers in children with moderate acute malnutrition.;Effect of corn-soy blend with vegetable oil and fish oil compared to corn-soy blend with vegetable oil alone on the composition of fecal microbiota.

—

Secondary

Measure	Time frame
Comparison of recovery and growth rates among children with moderate acute malnutrition receiving either corn-soy blend with vegetable oil and fish oil or corn-soy blend with vegetable oil alone.;Plasma levels of long chain omega-3 PUFAs	—

Countries

Kenya

Contacts

Public ContactBeatrice Olack

Research Officer

olackb@gmail.com+254721262359

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026