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Evaluation of hemodynamic status and cardiac performance in neonates with persistent pulmonary hypertension on high-frequency oscillatory ventilation versus conventional ventilation before and after treatment

Evaluation of hemodynamic status and cardiac performance in neonates with persistent pulmonary hypertension on high-frequency oscillatory ventilation versus conventional ventilation before and after treatment

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202104624409011
Enrollment
60
Registered
2021-04-06
Start date
2021-04-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paediatrics

Interventions

high frequency oscillatory ventillation HFOV
convention ventilator

Sponsors

faculty of medicine of tanta university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ? Neonates with persistent pulmonary hypertension

Exclusion criteria

Exclusion criteria: ? Neonates with major congenital anomalies. ? Neonates with dysrhythmias. ? Neonates with chest deformities. ? Maternal diabetes. ? Neonates with congenital heart disease except for small defects such as PDA or ASD. ? Neonatal sepsis cases. ? Evidence of perinatal asphyxia with Apgar score <5 at 5 minutes. ? Neonates with hydrops fetalis. ? All surgical cases. ? Neonates with severe intraventricular hemorrhage.

Design outcomes

Primary

MeasureTime frame
right ventricular output—

Secondary

MeasureTime frame
left ventricular output, pulmonary pressure, right ventricular diameter, left ventricular dimension and function, intraventricular hemorrhage, and mortality—

Countries

Egypt

Contacts

Public ContactDoaa El Amrousy

Associate professor of pediatrics

doaamoha@yahoo.com+0201289022229

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026