Cancer Skin and Connective Tissue Diseases
Conditions
Interventions
Chemotherapy with Scalp cooling
Sponsors
Nonhlanhla P Khumalo
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Female sex Age 18–65 years Removal of a breast cancer through mastectomy or breast conserving methods (with or without lymph node removal) < 12 weeks before inclusion Planned antineoplastic therapy with chemotherapy (Adriamycin and Cyclophosphamide followed by Paclitaxel) including written consent
Exclusion criteria
Exclusion criteria: Evidence of alopecia at baseline Planned radiation therapy of the skull before or during the study Antineoplastic therapy within 6 months prior to baseline Inadequately treated hypo or hyperthyroidism Known cold sensitivity, cold agglutinin disease, cryoglobulinemia and cryofibrinogenemia. Participation in another study. Unwillingness to participate in the study or withdrawal of consent before the first post treatment assessment. All post treatment data will be included in the analysis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To verify findings from previous research indicating that the severity of CIA is less in participants receiving scalp cooling versus those that are not, and to determine whether scalp cooling is less effective in patients with curly hair compared to those with straight hair. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess and establish procedures for recruitment and retention in a future study. | — |
Countries
South Africa
Contacts
Public ContactNonhlanhla Khumalo
Head of the department of Dermatology
Outcome results
None listed