Surgery
Conditions
Interventions
Intramuscular Morphine
Morphine and Paracetmol
Sponsors
Frank Enoch Gyamfi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients between 18 and 80 years of age. Patients undergoing emergency abdominal surgery Anticipated abdominal incision of at least 5cm long Patients who consent to take part in the study
Exclusion criteria
Exclusion criteria: Patients who are allergic to paracetamol or morphine Patients with impaired hepatic function or clinical features of liver disease Patients with renal impairment and CrCl < 60ml/min Patients with chronic opioid dependence Patients who are critically ill and may need ICU care Patients with a neuropsychiatric condition that may impair pain assessment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The efficacy of unimodal intravenous (i.v.) paracetamol and intramuscular (i.m.) morphine compared with bimodal administration of the two drugs in managing postoperative pain after emergency abdominal surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| The response of patients to i.v. paracetamol in pain management after emergency abdominal surgery;The response of patients to i.m. morphine in pain management after emergency abdominal surgery;The response of patients to a combination of i.v. paracetamol and i.m. morphine in managing pain after emergency abdominal surgery.;The association between the administered analgesic and length of hospital stay.;The association between administered analgesic and postoperative complications. | — |
Countries
Ghana
Contacts
Public ContactFrancis Aitpillah
Komfo Anokye Teaching Hospital
Outcome results
None listed