Surgery UTERINE FIBROIDS
Conditions
Interventions
Placebo with pericervical tourniquet
Misoprostol with pericervical tourniquet
Sponsors
Adebayo M.D. Agboola
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Patients presenting for abdominal myomectomy with documented uterine fibroids on pelvic imaging. 2. Age > 18years. 3. Pre-menopausal women 4. Pre-operative hematocrit >30% 5. Women willing to have sublingual administration of misoprostol or a placebo pre-procedure. 6. No other pre-operative medical intervention to reduce blood loss during abdominal myomectomy. 7. Consultant-led Abdominal myomectomy. 8. Regional anaesthesia for Abdominal myomectomy 9. Ability to understand and the willingness to sign a written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who have had a prior abdominal myomectomy 2. Post-menopausal women 3. Patients with a history of gynecologic malignancy 4. Patients with known bleeding/clotting disorders 5. Patients on anticoagulant therapy. 6. History of allergic reactions attributed to misoprostol or compounds of similar chemical or biologic composition to misoprostol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood loss at abdominal myomectomy | — |
Secondary
| Measure | Time frame |
|---|---|
| Need for blood transfusion;Post operative haematocrit;Duration of surgery;Febrile morbidity | — |
Countries
Nigeria
Contacts
Public ContactOladosu Ojengbede
Consultant
Outcome results
None listed