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Effect of Inverse ratio ventilation on hemodynamics and respiratory mechanics in obese patients undergoing laparoscopic sleeve gastrectomy.

Effect of Inverse ratio ventilation on hemodynamics and respiratory mechanics in obese patients undergoing laparoscopic sleeve gastrectomy.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202103499307292
Enrollment
52
Registered
2021-03-26
Start date
2018-04-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Surgery Anaesthesia

Interventions

inverse ratio ventilation group
volume control ventilation with normal ratio

Sponsors

Faculty of medicine Ain Shams University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.morbidly obese patients 2.for laparoscopic sleeve gastrectomy in reverse Trendelenburg position 3.from 21-45 years old, 4.ranging BMI between 35-50 kg/m2, 5.ASA II and III.

Exclusion criteria

Exclusion criteria: 1.patients with age more than 45 years and less than 21 years 2. BMI higher than 50kg/m2, 3. ASA class IV, severe intraoperative bleeding affecting hemodynamics, 4.operations that extended more than 60 minutes

Design outcomes

Primary

MeasureTime frame
volume-controlled inverse ratio ventilation (IRV) with inspiratory to expiratory (I:E) ratio of 2:1 could improve oxygenation as a primary outcome Lung mechanics readings including peak pressure (Ppeak), plateau pressure (Pplat), mean airway pressure (Pmean) were recorded every 10 minutes till end of the first hour, also dynamic and static compliance of the respiratory system were calculated after intubation and every 10 minutes until the end of the first hour. Static compliance = tidal volume /Pplateau-PEEP and Dynamic compliance= tidal volume/Ppeak-Peep

Secondary

MeasureTime frame
Hemodynamic parameters; Mean arterial blood pressure (MAP) heart rate (HR) were monitored at the start and all through the procedure and recorded before anesthesia induction (T0), immediately after intubation (T1), before pneumoperitoneum (T2), after pneumoperitoneum(T3) and then every 10 minutes till 60 minutes.

Countries

Egypt

Contacts

Public Contactmohammed saeed

professor

mohdsaeed47@yahoo.com00201002209759

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026