Corneal Collagen Cross-linking (CXL) versus Combined CXL and Femtosecond Laser-assisted Intra-corneal Ring Segment Implantation for Treatment of Keratoconus

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202102825518454

Enrollment

Registered

2021-02-22

Start date

2017-01-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases Surgery

Interventions

Corneal collagen crosslinking

Surgery

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Eyes with progressive keratoconus Presence of the clear central cornea. Corrected visual acuity (VA) of less than 20/40. Intolerance to contact lenses. A minimum central corneal thickness of 400 µm for the CXL procedure, and a minimum peripheral corneal is a thickness of 450 µm at the planned incision sites for ring implants. K reading values from 48 D - less than 65 D.

Exclusion criteria

Exclusion criteria: Severe keratconus (keratometric values of 65.0 D or more). Acute hydrops, corneal haze or opacity. Presence of active or recent ocular infection or inflammation. Collagen disease, and pregnancy or lactation during the study.

Design outcomes

Primary

Measure	Time frame
visual acuity;Refraction;Topographic outcomes	—

Secondary

Measure	Time frame
Contrast sensitivity ;Coma High order aberrations	—

Countries

Egypt

Contacts

Public ContactSeham Abdallah

Ministry of health

sehamabdallah83@yahoo.com00201014164955

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026