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The Possible Therapeutic Role of Intravenous Lipid Emulsion in Acute Aluminium Phosphide Poisoning: A Randomized Controlled Clinical Trial

The Possible Therapeutic Role of Intravenous Lipid Emulsion in Acute Aluminium Phosphide Poisoning: A Randomized Controlled Clinical Trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
PACTR
Registry ID
PACTR202102767216677
Enrollment
62
Registered
2021-02-11
Start date
2020-07-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injury, Occupational Diseases, Poisoning

Interventions

The standard treatment of aluminum phosphide Intoxication according to Tanta university poison treat

Sponsors

Hafsa Salah Gheat
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients aged = 12 years old. Either gender male or female. Symptomatic acute ALP poisoning. Diagnosis will be made on the basis of: 1. The suggestive clinical manifestations due to and following shortly after exposure to ALP. 2. Reliable identification of the compound based on the container brought by patient attendants 3. Biochemical detection of phosphine gas in gastric aspirate (silver nitrate test)

Exclusion criteria

Exclusion criteria: Patients less than 12 years old. Pregnant and lactating women. Patients with mixed ingestion or exposure. Patients with other major medical conditions (e.g. cardiovascular disease, renal or hepatic failure). Patients treated for acute phosphide poisoning in any medical center before admission. Patient with hyperlipidemia (serum triglyceride levels exceeds 400 mg/dL)

Design outcomes

Primary

MeasureTime frame
Mortality

Secondary

MeasureTime frame
Mean arterial blood pressure Need for intubation. Need for mechanical ventilation. The total dose of vasopressor needed. Duration of hospital stay. Serum lactate levels.

Countries

Egypt

Contacts

Public ContactManar Maher

Lecturer

Manarmaher85@gmail.com+201123558563

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026