Cholera
Conditions
Interventions
Two doses OCV administration
one OCV dose
Sponsors
Meilleur Acces aux Soins de Sante
International Department of Public Health Johns Hopkins University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age =1 year at the time of the 2017 OCV campaign, stratified into different age groups 2. Living in the Mogode Health Area where the OCV campaign was carried out 3. Good health condition, without clinically significant medical history (by participant or guardian, in case of minor) 4. Not pregnant for female subjects (confirmed by a urine pregnancy test) 5. Available to participate for the study duration, including all planned follow-up visits for up to 42 days from the time of screening. 6. Signed informed consent
Exclusion criteria
Exclusion criteria: 1. Presence of a significant medical or psychiatric condition (Examples include: Diagnosis and treatment of TB or HIV; renal insufficiency; hepatic disease; oral or parenteral medication known to affect the immune function , such as corticosteroids, other immunosuppressant drugs; or behavioural or memory issues) 2. Receipt of an investigational product (within 30 days before vaccination). 3. History of diarrhoea in 7 days prior to first dose of vaccine (defined as =3 unformed loose stools in 24 hours). 4. History of chronic diarrhea (lasting for more than 2 weeks in the past 6 months) 5. Current use of laxatives, antacids, or other agents to lower stomach acidity? 6. Planning to become pregnant in the next 2 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Early vibriocidal response | — |
Secondary
| Measure | Time frame |
|---|---|
| Geometric Mean titre of immune response | — |
Countries
Cameroon
Contacts
Public ContactJerome Ateudjieu
Executive Director of Meilleurs Acces aux Soins de Sante
Outcome results
None listed