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A novel drug combination and route for COVID-19 treatment

The use of topical (Nasal and oropharyngeal) Povidone iodine plus topical Glycyrrhizic acid and oral Glycyrrhizic acid syrup for prevention and treatment of early COVID-19 cases.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202101875903773
Enrollment
200
Registered
2021-01-25
Start date
2021-01-26
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corona virus

Interventions

Povidone Iodine plus Glycyhrrizic acid nasopharyngeal spray plus Glycyrrhizic acid syrup
Positive control group

Sponsors

Hazem Elsersy
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: COVID-19 PCR positive patients of both genders aging 6 to 70 years having no symptoms or early symptoms such as loss of taste and smell, fever, cough with good O2 saturation.

Exclusion criteria

Exclusion criteria: Patients with CT evidence category 4 or 5. Patients with dropped O2 saturation below 90 on room air. Patients with uncontrolled hypertension or diabetes mellitus. Ventilated patients or those with multiorgan failure.

Design outcomes

Primary

MeasureTime frame
The primary outcome will be the PCR result for corona virus on day 4 and day 10. This will be done for the early treatment experiment;number of treated close contacts getting infected with corona virus in both groups

Secondary

MeasureTime frame
The post-treatment day that the fever subsides; the post-treatment day for return of taste and smell ;The post-treatment day that the cough subsides;Number of patients needed hospitalization.;the number of deaths in both groups

Countries

Egypt

Contacts

Public ContactDr. Magdy Zahran

Professor of organic chemistry Faculty of science Menofia University.

magdyzahran@gmail.com00201007208275

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026