Role of diazepam in treatment of organophosphorus pesticides poisoning

Role of diazepam in treatment of organophosphorus pesticides poisoning: A randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202101718826859

Enrollment

100

Registered

2021-01-21

Start date

2017-01-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injury, Occupational Diseases, Poisoning

Interventions

Diazepam

saline

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Symptomatic patients Exposd to organophosphorus pesticides > 18 years old

Exclusion criteria

Exclusion criteria: Pregnant and lactating patients. Patients <18 years old. Patients who developed seizures after organophosphate poisoning. Patients with mixed ingestions. Epileptic patients or Patients with other neurological disorders. Patients with other serious medical conditions (e.g. cardiovascular disease, renal or hepatic failure). Patients who received treatment before admission

Design outcomes

Primary

Measure	Time frame
Mortality, neurological comlpicatons	—

Secondary

Measure	Time frame
The total dose of atropine required. Seizures: occurrence, response to treatment Electroencephalograph findings. Duration of hospital stay for live discharges. Need for mechanical ventilation. Intermediate syndrome	—

Countries

Egypt

Contacts

Public ContactEman Soliman

Department of Forensic Medicine and Clinical Toxicology Faculty of Medicine Tanta University

dr.emansoliman1960@gmail.com+201005621611

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026