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Evaluation of The Therapeutic Role of Coenzyme Q10 and Coconut Oil in Acute Aluminum Phosphide Poisoning Outcomes:A Randomized Controlled Clinical Trial

Evaluation of The Therapeutic Role of Coenzyme Q10 and Coconut Oil in Acute Aluminum Phosphide Poisoning Outcomes:A Randomized Controlled Clinical Trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
PACTR
Registry ID
PACTR202101703883803
Enrollment
84
Registered
2021-01-20
Start date
2020-11-28
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injury, Occupational Diseases, Poisoning

Interventions

the standered supportive care plus lavage with coconut oil and Coenzyme Q10
The standered treatment
the standered supportive measurements plus coconut oil

Sponsors

Rasha Elhussieny Elsharkawy
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All acute ALP poisoned patients of both sexes admitted to Tanta university poison control center within 6 hours delay after ingestion and fit for gastric lavage will be enrolled in this study.

Exclusion criteria

Exclusion criteria: • Asymptomatic patients • Pregnant and lactating women • Patients with combined drug/chemical ingestion in addition to aluminum phosphide. • Patients with chronic diseases (e.g. cardiovascular disease, renal or hepatic failure, infection, and cancer). • Patients with a disturbed consciousness level • Patients with post-cardiac arrest patients with ALP inhalation Patents with previous medical interventions before coming

Design outcomes

Primary

MeasureTime frame
mortality rate

Secondary

MeasureTime frame
• Need for intubation and mechanical ventilation. • Need for ICU admission • Duration of hospital stay • Total dose of needed inotropes

Countries

Egypt

Contacts

Public ContactMona Ghonaim

ass.prof of forensic medicine and clinical toxicology

mona.ghonaim@med.tanta.edu.eg00201064257070

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026