Prophylactic effect of colchincine and amiodarone

Prophylactic Effect of colchincine and amiodarone on occurrence of postoperative Atrial fibrillation after coronary artery bypass Graft surgery

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202101651961317

Enrollment

100

Registered

2021-01-21

Start date

2019-12-01

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiology

Interventions

Controlled group

Colchincine group

Amiodarone group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: • Patients undergoing elective coronary artery bypass surgery

Exclusion criteria

Exclusion criteria: • Emergency CABG. • Patients with chronic renal failure as diagnosed by serum creatinine level above 200µmol/l. • Patient undergoing CABG combined with valve surgery. • Patients undergoing Re-Do CABG. • Patients with history of atrial fibrillation determined by previous records. • Patients with known hypersensitivity-allergy to colchicine or amiodarone. • Under chronic treatment with colchicine or amiodarone.

Design outcomes

Primary

Measure	Time frame
evaluation preventive role of colchicine and amiodarone against atrial fibrillation after coronary artery bypass grafting.	—

Secondary

Measure	Time frame
effect on Intensive care stay and hospital stay	—

Countries

Egypt

Contacts

Public ContactAlaa;Ayman Basiony;Sallam

Professor of cardiothoracic ;Professor of cardiothoracic

Alaabasionuni@yahoo.com;Ayman_sal@hotmail.com00201011323710;00201098121122

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026