Skip to content

EFFECT OF INTRAVENOUS TRANEXAMIC ACID IN REDUCING BLOOD LOSS DURING AND AFTER ELECTIVE CAESAREAN SECTION IN THE UNIVERSITY OF PORT HARCOURT TEACHING HOSPITAL: A RANDOMIZED CONTROLLED STUDY

EFFECT OF INTRAVENOUS TRANEXAMIC ACID IN REDUCING BLOOD LOSS DURING AND AFTER ELECTIVE CAESAREAN SECTION IN THE UNIVERSITY OF PORT HARCOURT TEACHING HOSPITAL: A RANDOMIZED CONTROLLED STUDY

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
PACTR
Registry ID
PACTR202011872201172
Enrollment
148
Registered
2020-11-20
Start date
2020-06-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood loss during and after caesarean section

Interventions

intravenous tranexamic acid
placebo

Sponsors

JEMIRIGBE OMAWUMI DARLINGTON
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Age between 20 to 40 years. Parity- 1 - 4 Gestational age of 37-40 weeks. Singleton live fetus with reassuring fetal heart rate. Elective repeat CS.

Exclusion criteria

Exclusion criteria: Refusal of the patient to give consent. Known allergy to intravenous tranexamic acid. Multiple pregnancies. Antepartum haemorrhage. Co-existing uterine fibroids. Macrosomic baby- birth weight =4kg. Intrauterine fetal death. Preeclampsia. Others are history of thromboembolic disease, medical conditions such as major liver, heart, kidney, brain and bleeding disorders, anticoagulant therapy, patients requiring blood transfusion due to anaemia and polyhydramnios. The medical conditions will be excluded from thorough history and examination of the patient and those with a positive history and examination findings suggestive of these medical conditions will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
Amount of blood loss during and after caesarean section.

Secondary

MeasureTime frame
Additional uterotonic drugs.;2. Blood transfusion. ;3. Surgical interventions.;Maternal and fetal side effects.

Countries

Nigeria

Contacts

Public ContactOmawumi Jemirigbe

Senior Registrar

owumi2012@yahoo.com08034059131

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026