hemodynamic effect of ondasterone in parturients undergoing cesarean section

Effect of prophylactic ondansetron for prevention of spinal induced hypotension and bradycardia in parturients undergoing elective cesarean delivery under spinal anesthesia, a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

PACTR

Registry ID

PACTR202011750758363

Enrollment

112

Registered

2020-11-30

Start date

2020-12-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery Fertility-female Anaesthesia

Interventions

ondasterone

saline

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Age between 18-35 years(67) ASA physical status class II

Exclusion criteria

Exclusion criteria: • Hypersensitivity to ondansetron • History of Hypertensive disorders, anemia, Heart disease, diabetes, and placenta previa • Patient receiving selective serotonin reuptake inhibitor or migraine medication • Obesity (BMI =29-35 kg/m2) (69) • Height <155 cm(70)

Design outcomes

Primary

Measure	Time frame
hypotension and bradycardia	—

Secondary

Measure	Time frame
side effects of ondasterone	—

Countries

Ethiopia

Contacts

Public ContactDerartu Neme

lecturer

dereneme.emma@gmail.com+251913386656

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026