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A randomised controlled trial of TF-CBT in South African adolecents

A randomised controlled trial of TF-CBT in South African adolecents

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
PACTR
Registry ID
PACTR202011506380839
Enrollment
84
Registered
2020-11-25
Start date
2016-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental and Behavioural Disorders

Interventions

Traumafocused CBT or TFCBT
Enhanced treatment as usual or enhanced TAU

Sponsors

Debra Kaminer
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Participants must have been exposed to a traumatic event according to the DSM 5 PTSD Criterion A. Participants must meet criteria for a clinical or subclinical diagnosis of PTSD according to the DSM-5, as assessed using the KSADS-PL and the CPSS-5. Subclinical PTSD is defined as having at least 1 re-experiencing symptom, at least 2 avoidance symptoms, 2 arousal symptoms and/or a score of at least 21 on the CPSS-5. Adolescents with both acute (1-3 months post-trauma) and chronic (>3 months post-trauma) PTSD will be included into the study, given that the evidence for TF-CBT shows benefit for both acute and chronic groups. Provided that PTSD is the primary disorder requiring treatment, adolescents with comorbid mood disorders, anxiety disorders, substance use disorders and behavioural disorders (of oppositional defiant disorder, conduct disorder or and attention-deficit/hyperactivity disorder) and sub-clinical substance misuse will be included. At least six years of formal education. Proficiency in English or Afrikaans.

Exclusion criteria

Exclusion criteria: Intellectual disability or autism spectrum disorder Psychotic disorder High suicide risk Clinically significant alcohol or substance abuse

Design outcomes

Primary

MeasureTime frame
PTSD diagnosis as assessed on the K-SADS PL;PTSD symptom severity as assessed by the CPSS 5

Secondary

MeasureTime frame
Major depressive disorder assessed with the K-SADS PL;Severity of depression symptoms assessed with the Beck Depression Inventory II;Severity of aggression symptoms assessed with the Aggression Questionnaire

Countries

South Africa

Contacts

Public ContactDebra Kaminer

Associate Professor University of Cape Town Psychology Department

debbie.kaminer@uct.ac.za+27216503900

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026