Severe hypertension in pregnancy Cardiology
Conditions
Interventions
Sponsors
MUHAMMAD Sagir
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: • Consenting pregnant women with severe hypertension in pregnancy with systolic blood pressure (SBP) of at least 160 mmHg and/or diastolic blood pressure (DBP) of at least 110 mmHg. • Gestational age of 28 weeks or more which will be determined based on ultrasound scan or last menstrual period. • Live singleton fetus with normal fetal heart rate.
Exclusion criteria
Exclusion criteria: • All women with cardiac disease such as heart block, ischaemic heart disease, and hypertensive cardiac disease. • Asthma • History of allergy to either hydralazine or labetalol. • Chronic medical disorder such as chronic kidney disease and diabetes mellitus. • Women with haemoglobinopathy such as HbSS. • Multiple gestation. • Preterm labour at gestational age of less than 34 weeks • Women who are already on other antihypertensive drugs. • Patients with stroke • Unconscious patients • Patients with HELLP syndrome and liver disease • Presence of fetal distress • Non consenting women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean reduction in Mean Arterial Blood Pressure and rate of Persistent hypertension | — |
Secondary
| Measure | Time frame |
|---|---|
| Perinatal outcome and maternal sideeffects | — |
Countries
Nigeria
Contacts
Public ContactSAGIR MUHAMMAD
DEPARTMENT OF OBS AND GYNAE SPECIALIST HOSPITAL GOMBE
Outcome results
None listed