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In vivo and in vitro anti-hookworm effect of Single dose of Albendazole among outpatients at Adet primary Hospital, Northwest, Ethiopia

In vivo and in vitro anti-hookworm effect of Single dose of Albendazole among outpatients at Adet primary Hospital, Northwest, Ethiopia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
PACTR
Registry ID
PACTR202010511829332
Enrollment
50
Registered
2020-10-26
Start date
2020-02-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hookworm infections

Interventions

Albendazole Efficacy
albendazole efficacy

Sponsors

Amhara Regional Health Bureau
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ? All outpatients agree to comply with study procedures, including the provision of two enough stool samples at the beginning (baseline) and at post-treatment follow up assessments (approximately 2 weeks, later). ? All hookworm positive study participants > 2 years old ? Both sex (female and male ) hookworm positive participants

Exclusion criteria

Exclusion criteria: ? Pregnant women ? Patients undertake anthelminthic drugs during data collection time within the past 6 weeks) ? Participants with medication with known interaction (e.g. for albendazole: cimetidine, praziquantel, and dexamethasone) ? Patients who had a history of severe chronic disease (e.g.cancer, diabetes, chronic heart, liver or renal disease). ? Participants having diarrhea or vomiting

Design outcomes

Primary

MeasureTime frame
Cure rate and egg reduction rates of single doses of albendazole were the primary outcomes of this study

Secondary

MeasureTime frame
MIC of albendazole killing effects for hookworm larva in culture media

Countries

Ethiopia

Contacts

Public ContactAyalew Jejaw

Department of Medical Parasitology School of Biomedical and Laboratory Sciences College of Medicine and Health sciences University of Gondar

ayalewjejaw@gmail.com+251910208492

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026