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Sublingual Misoprostol Versus Manual Vacuum Aspiration for Treatment of Incomplete Abortion in Nigeria: A Randomized Control Study

Misoprostol for incomplete miscarriage

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202009857889210
Enrollment
212
Registered
2020-09-23
Start date
2014-08-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth

Interventions

immediate manual vacuum aspiration in the theater by trained medical practitioners

Sponsors

None listed

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: All consenting women at the study centres with first-trimester incomplete abortion, confirmed by a trans-abdominal ultrasound scan of the uterus, were eligible for the study

Exclusion criteria

Exclusion criteria: Women with excessive vaginal bleeding, severe anaemia (Hb < 7.0g%), or suspected ectopic pregnancy were excluded from the study. A history of allergy to prostaglandins, Evidence of genital infection such as offensive vaginal discharge, uterine tenderness, and pyrexia.

Design outcomes

Primary

MeasureTime frame
The primary outcome measure was the incidence of complete uterine evacuation (complete abortion) after one week of treatment with single-dose sublingual misoprostol 400mcg or MVA.

Secondary

MeasureTime frame
The secondary outcome measures included incidence, types, and tolerability of treatment side effects as well as participants’ satisfaction with the treatment received

Countries

Nigeria

Contacts

Public ContactCyril Chukwudi Dim

Consultantt

cyril.dim@unn.edu.ng+2348033341960

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 13, 2026