Anaesthesia
Conditions
Interventions
DEXMEDETOMIDINE GROUP
Sponsors
RHONA
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: American Society of anaesthesiologists physical status classification: (ASA) ASA I which represents a normal healthy patient. ASA II represents a patient with mild systemic disease. age 18 – 50 male and female A patient presenting for lower limb surgery, whether for an emergency procedure or an elective procedure.
Exclusion criteria
Exclusion criteria: Patient refusal Known allergy to Bupivacaine or Dexmedetomidine Pregnancy Lactating Mothers Cardiopulmonary abnormalities Hepatic or renal abnormalities Patient on anticoagulation therapy Spinal cord deformities Local skin site infections Heart block or dysrhythmias Asthma Morbid Obese patient Patients with obstructive sleep apnoea
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare side effects for both agents observed intra-operatively and post-operatively, which include: ?Hypotension ?Bradycardia ?Respiratory depression ?Pruritis ?Nausea and vomiting | — |
Secondary
| Measure | Time frame |
|---|---|
| ? To compare the adequacy of post-operative pain control of both agents. ? To compare the duration of post-operative pain control by evaluating time to first rescue analgesia in the ward. ? To compare the onset time of spinal anaesthesia by evaluating time to reach dermatome level T10 for both agents. | — |
Countries
South Africa
Contacts
Public ContactRHONA GOUWS
ANAESTHESIA REGISTRAR
Outcome results
None listed