Hemoperfusion for organophosphate poisoning in critically ill patients- A randomized trial.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202009754904918

Enrollment

Registered

2020-09-16

Start date

2020-01-06

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injury, Occupational Diseases, Poisoning

Interventions

Haemoperfusion

Standard care

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All adult patients admitted to the ICU with a diagnosis of organophosphate poisoning will be included. Age =18 years Consistent History Cholinergic toxidrome Patient recruitment within 12 hours of ICU admission Written informed consent

Exclusion criteria

Exclusion criteria: Patients with polypharmacy overdoses were excluded Patients with a contra-indication to anticoagulation with heparin and enoxaparin

Design outcomes

Primary

Measure	Time frame
ICU length of Stay	—

Secondary

Measure	Time frame
Mortality ;Serum Organophosphate and Carbamate levels;Cost of ICU stay;Duration and Dose of antidote;Duration of Organ support;Motor Score;Complications	—

Countries

South Africa

Contacts

Public ContactAyesha Khan

Paediatric Intensivist

Ayesha.Khan@wits.ac.za+27825503102

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026