COMPARISON OF SINGLE VERSUS MULTIPLE DOSE (AMOXICILLIN/CLAVULANIC ACID) ANTIMICROBIAL PROPHYLAXIS FOR CAESAREAN SECTION IN FEDERAL TEACHING HOSPITAL GOMBE, NIGERIA - A RANDOMIZED CONTROLLED TRIAL

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202009483150226

Enrollment

176

Registered

2020-09-07

Start date

2019-07-22

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postcaesarean surgical site infection

Interventions

Single dose Preincision Amoxicillin Clavulanic acid

Multiple doses of Amoxicillin Clavulanic acid

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: • Pregnant women booked for elective or emergency caesarean delivery • Patients who gave informed consent

Exclusion criteria

Exclusion criteria: • Women with immunosuppression such as those with HIV infection and uncontrolled diabetes mellitus • Features of chorioamnionitis such as foul-smelling lochia, tender uterus and fever • Moderate to severe anaemia (haemoglobin concentration less than 8g/dl) or packed cell volume (PCV) of less than 24%. • Ruptured membranes more than 8 hours • Active phase of labour more than 8 hours • Multiple vaginal examinations (more than 3) • Known allergy to any of the drugs to be used

Design outcomes

Primary

Measure	Time frame
Occurrence of surgical site infection	—

Secondary

Measure	Time frame
Occurence of Urinary Tract Infection	—

Countries

Nigeria

Contacts

Public ContactSagir Muhammad

Senior Registrar

sagirmuhammad2013@gmail.com2348034309414

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026