Surgery hystrectomy Anaesthesia
Conditions
Interventions
control group
Sponsors
suez canal university hospital
anaesthesia departement faculty of medicine suez canal university
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Patients aged 40-60 years. 2. Patients are ASA I or ASA II 3. Patients scheduled for abdominal hysterectomy
Exclusion criteria
Exclusion criteria: 1) Pre-operative regular medication with opioids and benzodiazepines, alcohol abuse, known sleep disturbance, known endocrine disease 2) Patient refusal to participate in the study 3) Known allergy to lidocaine 4) History of uncontrolled hypertension or diabetes mellitus, and other endocrine disorders 5) Heart block greater than first degree 6) use of medication known to affect the sympathetic response or hormonal secretion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the effect of perioperative lidocaine infusion on the level of IL 6. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cortisol level;intraoperative hemodynamics , heart rate and blood pressure;postoperative hemodynamics heart rate blood pressure;intraoperative fentanyl consumption;Postoperative 1st request of analgesia;intraoperative isoflurane consumption;The total amount of ephedrine or atropine given because of hypotension or bradycardia ;Total morphine consumption during the 1st 24hrs postoperative by PCA;postoperative VAS pain score at rest and during cough | — |
Countries
Egypt
Contacts
Public Contactahmed eliwa
lecturer of anesthesia
Outcome results
None listed