Effectiveness of Ketofol versus Propofol Induction on Hemodynamic Profiles in Adult Elective Surgical Patients: - A Double Blind Randomized Controlled Trial.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

PACTR

Registry ID

PACTR202008628465772

Enrollment

125

Registered

2020-08-18

Start date

2020-08-14

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Propofol

Ketofol

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - ASA I and II - Age 18-65 years

Exclusion criteria

Exclusion criteria: - Obstetric, Neurosurgical and ENT surgery are excluded - Those on long time opioid use/ sedative preoperative adjunctive medications - Those who use psychotropic drugs - any known contraindications/allergy to ketamine or propofol - pre-operative anxious patients - patient in pain

Design outcomes

Primary

Measure	Time frame
Our primary endpoints were a change in hemodynamic parameters (MAP, SBP, and HR) from baseline immediately after induction, 5 minutes, 10 minutes, 15 minutes, 20 minutes, 25 minutes, and 30 minutes	—

Secondary

Measure	Time frame
Secondary endpoints include postoperative pain, nausea, and vomiting incident was graded and recorded in the PACU.	—

Countries

Ethiopia

Contacts

Public ContactSileshi Hailu

first advisor

abebihailu911@gmail.com+2510913785100

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026