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AFRO II Demonstration Project

Evaluating the feasibility and impact of community-based house screening as an additional vector control intervention on malaria transmission in southern Africa: A study protocol for a household randomized demonstration study.

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
PACTR
Registry ID
PACTR202008524310568
Enrollment
2400
Registered
2020-08-11
Start date
2017-06-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malaria

Interventions

House screening arm
Control arm

Sponsors

World Health Organization Regional Office for Africa
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: • Houses are partly modern with potential spaces for mosquito entry and screening potential. • Houses are at least 50 meters apart • Houses have at least 2 children between 6 months and 13 years of age that reside and sleep in them.

Exclusion criteria

Exclusion criteria: • Houses in which potential spaces for mosquito entry are screened. • Houses are less than 50 meters apart • Houses that do not have at least 2 children between 6 months and 13 years of age that reside and sleep in them.

Design outcomes

Primary

MeasureTime frame
Vector adult density inside and outside screened houses will be compared with houses that use LLINs alone.;Clinical malaria in children between 6 months and 13 years measured using rapid diagnostic tests, dry blood spots and thick and thin blood smears in screened houses compared to houses that use LLINs only.;Assess the incremental cost of house screening in houses where this intervention has been implemented.

Secondary

MeasureTime frame
Sporozoite rates, human biting index and entomological inoculation rates both indoors and outdoors in screened houses will be compared to houses that use LLINs alone.;Parasite infection rate and parasite density in children between 6 months and 13 years in screened houses compared to houses that use LLINs only.;1. Evaluate the acceptability of house screening as a malaria control tool in the community. 2. Identify the barriers and opportunities for scale of house screening and advocate for the adoption of this intervention as a policy in national malaria control programmes of the study countries.

Countries

Mozambique, Zambia, Zimbabwe

Contacts

Public ContactPeter;Theresia Sangoro;Nkya

Postdoctoral Research Fellow;Postdoctoral Research Fellow

psangoro@icipe.org;tnkya@icipe.org+254208632098;+254208632254

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026