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TRACE - Transmission of Covid-19 in Crowded Environments

TRACE - Transmission of Covid-19 in Crowded Environments

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202008485004797
Enrollment
720
Registered
2020-08-06
Start date
2020-08-03
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory

Interventions

Enhanced usual care

Sponsors

Desmond Tutu Health Foundation
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Eligibility of index case inclusion: Individual >12 years Able to give assent if 18 years Self-isolating at home at the time of COVID diagnosis Eligibility of household contact inclusion: Living in the same household as index case Able to give assent if 12-17 years with parental/guardian consent Able to give consent= 18 years

Exclusion criteria

Exclusion criteria: Index case exclusion: <12 years Unable to give consent household contact exclusion: Unable to give consent

Design outcomes

Primary

MeasureTime frame
SARS-CoV-2 transmission will be monitored using nasopharyngeal swabs for SARS- CoV-2 PCR and serology (IgM/IgG) assays in all household contact weekly for 1 month. Symptom checklists will be completed daily and collated weekly for each household contact.

Secondary

MeasureTime frame
The proportion of transmissions to HHC in the households of COVID cases assigned to the infection mitigation intervention arm compared with the households in the enhanced usual care (EUC) arm.

Countries

South Africa

Contacts

Public ContactPhilip Smith

Scientist

Philip.Smith@hiv-research.org.za0838602289

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026