Respiratory
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Eligibility of index case inclusion: Individual >12 years Able to give assent if 18 years Self-isolating at home at the time of COVID diagnosis Eligibility of household contact inclusion: Living in the same household as index case Able to give assent if 12-17 years with parental/guardian consent Able to give consent= 18 years
Exclusion criteria
Exclusion criteria: Index case exclusion: <12 years Unable to give consent household contact exclusion: Unable to give consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SARS-CoV-2 transmission will be monitored using nasopharyngeal swabs for SARS- CoV-2 PCR and serology (IgM/IgG) assays in all household contact weekly for 1 month. Symptom checklists will be completed daily and collated weekly for each household contact. | — |
Secondary
| Measure | Time frame |
|---|---|
| The proportion of transmissions to HHC in the households of COVID cases assigned to the infection mitigation intervention arm compared with the households in the enhanced usual care (EUC) arm. | — |
Countries
South Africa
Contacts
Scientist