Rehabilitation for women with breast cancer undergoing ajduvant chemotherapy.

Characterization of muscle fatigue, rehabilitation and quality of life in a population with breast cancer.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

PACTR

Registry ID

PACTR202007730554581

Enrollment

Registered

2020-07-01

Start date

2016-05-11

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer

Interventions

Aerobic and Strength program

No intervention

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: - Women aged from 18 to 65 years. - No known history of chronic respiratory, cardiac or neuromuscular disease. - Diagnosed with non-metastatic breast cancer (stage y–IIIA). - Women who have had a mastectomy and are in the process of adjuvant chemotherapy (postoperative).

Exclusion criteria

Exclusion criteria: - Hemoglobin concentration 30]. - Malnutrition (BMI 50 mg/day or equivalent dose of related agents). - Chronic infection, neurological or muscular impairment. - chronic diseases that could be exacerbated by exercise (coronary artery disease, chronic obstructive pulmonary disease, osteoarthritis), skeletal metastases resulting in bone instability, or progressive disease

Design outcomes

Primary

Measure	Time frame
Compared to controls, we mentioned a positive effects of our training protocol on the aerobic fitness and metabolic needs of our trained patients. A significant increases in MViC, ET in an isometric test, and muscle deoxygenating ?HHb. In addition, we observed an improvement in the myoelectric activity of the Vastus lateralis, characterized by the decrease of the RMS and the increase of the MPF during the holding phase of 50% of the MViC, in the trained group after the six weeks combined aerobic training and muscle strengthening. Finally , we observed a significant improvement in the quality of life of the trained group. This improvement is characterized, on the one hand, by an increase in the overall quality of life and scores at the functional scales, and on the other hand by a reduction in the scores of symptom scales in cancer patients treated with adjuvant chemotherapy	—

Measure

Time frame

Compared to controls, we mentioned a positive effects of our training protocol on the aerobic fitness and metabolic needs of our trained patients. A significant increases in MViC, ET in an isometric test, and muscle deoxygenating ?HHb. In addition, we observed an improvement in the myoelectric activity of the Vastus lateralis, characterized by the decrease of the RMS and the increase of the MPF during the holding phase of 50% of the MViC, in the trained group after the six weeks combined aerobic training and muscle strengthening. Finally , we observed a significant improvement in the quality of life of the trained group. This improvement is characterized, on the one hand, by an increase in the overall quality of life and scores at the functional scales, and on the other hand by a reduction in the scores of symptom scales in cancer patients treated with adjuvant chemotherapy

—

Secondary

Measure	Time frame
Concentration and rating of perceived exertion (RPE), Before and after six weeks of training program.	—

Countries

Tunisia

Contacts

Public ContactAMEL MEZLINI

Medical oncology service Director

amel.mezline@rns.tn+21671150792

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026