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Role of granulocyte colony stimulating factor or human chorionic gonadotropin in improving embryo implantation

Effect of intra uterine human chorionic gonadotropin versus granulocyte colony stimulating factor at ovum pick up Day in cases of recurrent implantation failure

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202006915851110
Enrollment
150
Registered
2020-06-30
Start date
2019-01-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fertility-female

Interventions

Sponsors

Wald we bent center
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: women aged 20-43 years old undergoing ICSI cycles history of recurrent implantation failure at least 1 cycle in which she had day 5 embryo transfer

Exclusion criteria

Exclusion criteria: Women with renal sickle cell disease history of malignancy history of poor quality embryos risk of Ovarian hyperstimulation syndrome (OHSS)

Design outcomes

Primary

MeasureTime frame
clinical pregnancy rate (defined as viable pregnancy when there is evidence of gestational sac, embryo and fetal heart activity at time of trans-vaginal ultrasound evaluation by the 8th week) ;implantation rate (defined as the number of gestational sacs observed at echographic screening at 6 weeks of pregnancy divided by the number of embryos transferred).

Secondary

MeasureTime frame
Biochemical pregnancy rate (defined as positive from quantative values of serum test of ß-hCG according to the standard values used in the laboratory at second week) ;miscarriage rate (defined as the loss of pregnancy before 8th weeks‘ gestational age

Countries

Egypt

Contacts

Public ContactMohamed Abd ElGawad

Medical student at faculty of medicine Fayoum university

mohammed.mahmod87@gmail.com+201069401202

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026