COVID-19 Respiratory
Conditions
Interventions
Sponsors
Dar Al Fouad Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? Age 18-80 years old ? Subjects who are willing to comply with the requirements of the study protocol and scheduled visits (for example, completion of the subject diary, return for follow-up visits) and who are willing to make themselves available for the duration of the study with access to a consistent means of telephone contact,
Exclusion criteria
Exclusion criteria: ? Acute severe illness ? Recent receipt of a blood product ? History of thrombocytopenia ? Pregnant females ? Any chronic medical condition ? Any participant receiving any immune suppressive medication ? Immunocompromised staff ? Participants who have egg allergy ? Participants who care for immune compromised hosts at home ? Participants who had documented COVID-19 either by RT-PCR or radiologically in the past six months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. COVID-19 incidence [ Time Frame: Measured over the 6 months following randomization] 2. Number of participants with asymptomatic or mild COVID-19 disease defined as I.fever (using a self-reported questionnaire), plus II.at least one sign or symptom of respiratory disease including cough, runny/blocked nose (using self-reported questionnaire), plus III.positive SARS-Cov-2 test (PCR or serology) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. SARS-CoV-2 pneumonia [ Time Frame: Measured over the 6 months following randomization] 2. Number of pneumonia cases (abnormal chest X-ray) (using a self-reported questionnaire and/or medical/hospital records) associated with a positive SARS-CoV-2 test 3. Critical care admission duration with SARS-CoV-2 [ Time Frame: Measured over the 6 months following randomization] 4. Number of days admitted to critical care (using a self-reported questionnaire and/or medical/hospital records) associated with a positive SARS-CoV-2 test 5. Oxygen therapy with SARS-CoV-2 [Time Frame: Measured over the 6 months following randomization] 6. Need for oxygen therapy (using a self-reported questionnaire and/or medical/hospital records) associated with a positive SARS-CoV-2 test 7. Critical care admissions with SARS-CoV-2 [Time Frame: Measured over the 6 months following randomization]. 8. Number of admission to critical care (using a self-reported questionnaire and/or medical/hospital records) associated with a positive SARS-CoV-2 test | — |
Countries
Egypt
Contacts
Public ContactHend;Doaa Ibrahim;Nagy
Pharmacist;Pharmacist
Outcome results
None listed