Interrupted Direct Current stimulation, for Neuromuscular Recovery and Return to Walking after Traumatic Spinal cord injury : a Randomised Control Trial

Interrupted Direct Current stimulation for Neuromuscular Recovery and Return to Walking after Traumatic Spinal cord injury : a Randomised Control Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202006840710922

Enrollment

Registered

2020-06-23

Start date

2018-06-09

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injury, Occupational Diseases, Poisoning Nervous System Diseases Surgery Spinal cord injury

Interventions

Interrupted Direct Current plus Functional reeducation approach

Functional reeducation approach

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Individuals diagnosed with traumatic spinal cord injury (TSCI). Individuals with TSCI located at the fourth cervical vertebral level (C4) and below. Individuals with TSCI who can be assessed within one month of SCI injury or within the period of spinal shock.

Exclusion criteria

Exclusion criteria: Individuals diagnosed with TSCI with progressive, or potentially progressive, spinal lesions including cancer and degenerative, or progressive vascular disorders of the spine and/or spinal cord. Individuals diagnosed with TSCI and other pre-morbid neurological conditions. Individuals diagnosed with altered cognitive status.

Design outcomes

Primary

Measure	Time frame
The American Spinal Injury Association: International Standards for Neurological Classification of Spinal Cord Injury. This instrument is used to establish the neurological level of injury, as well as the severity of the lesion or impairment and rectal examination for voluntary anal contraction and anal sensation, in patients with SCI, using the following categories: A=Complete: No sensory or motor function is preserved in sacral segments S4-S5 B = Incomplete: Sensory, but not motor function is preserved below the neurologic level and extends through sacral segments S4-S5. C= Incomplete: Motor function is preserved below the neurologic level, and most key muscles below the neurologic level have a muscle grade of less than 3. D=Incomplete: Motor function is preserved below the neurologic level, and most key muscles below the neurologic level have a muscle grade that is greater than or equal to 3. E = Normal: Sensory and motor functions are normal. Use of the ASIA scale will assure uniformity in the patient population ;The Walking Index for Spinal Cord Injury II. The purpose of this scale is for use in clinical trials to measure improvements in walking in persons with spinal cord injury. The following outline describes subjects for whom the scale is most commonly utilized. 1.Spinal cord injury subjects who are capable of standing and walking in the parallel bars will be eligible for assessment. Only a reciprocal gait is to be considered in scoring the WISCI scale. Additional inclusion/exclusion criteria may be necessary. 2.Most often ASIA A below T10 and ASIA B, C, and D subjects may qualify. 3.Individuals with tetraplegia would require motor strength in triceps of at least grade 3 or be able to support their body weight. Standardized Physical Environment and Distance This is a functional limitation scale, not a disability scale. It must be used in a standardized environment with standardize	—

Measure

Time frame

The American Spinal Injury Association: International Standards for Neurological Classification of Spinal Cord Injury. This instrument is used to establish the neurological level of injury, as well as the severity of the lesion or impairment and rectal examination for voluntary anal contraction and anal sensation, in patients with SCI, using the following categories: A=Complete: No sensory or motor function is preserved in sacral segments S4-S5 B = Incomplete: Sensory, but not motor function is preserved below the neurologic level and extends through sacral segments S4-S5. C= Incomplete: Motor function is preserved below the neurologic level, and most key muscles below the neurologic level have a muscle grade of less than 3. D=Incomplete: Motor function is preserved below the neurologic level, and most key muscles below the neurologic level have a muscle grade that is greater than or equal to 3. E = Normal: Sensory and motor functions are normal. Use of the ASIA scale will assure uniformity in the patient population ;The Walking Index for Spinal Cord Injury II. The purpose of this scale is for use in clinical trials to measure improvements in walking in persons with spinal cord injury. The following outline describes subjects for whom the scale is most commonly utilized. 1.Spinal cord injury subjects who are capable of standing and walking in the parallel bars will be eligible for assessment. Only a reciprocal gait is to be considered in scoring the WISCI scale. Additional inclusion/exclusion criteria may be necessary. 2.Most often ASIA A below T10 and ASIA B, C, and D subjects may qualify. 3.Individuals with tetraplegia would require motor strength in triceps of at least grade 3 or be able to support their body weight. Standardized Physical Environment and Distance This is a functional limitation scale, not a disability scale. It must be used in a standardized environment with standardize

—

Secondary

Measure	Time frame
Thigh Girth and Calf Girth is measured with the use of a measuring tape. The thigh girth is taken at 25 centimeters from the anterior superior iliac crest while the calf girth is taken at a point 25 centimeters from the lateral malleolus. This is to assess any changes in muscle bulk during the period of the study.	—

Countries

Nigeria

Contacts

Public ContactOlajide Olawale

Professor and Supervisor

oolawale@unilag.edu.ng+2348080774586

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026