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ALERT – Action Leveraging Evidence to reduce perinatal Mortality and morbidity in Sub-Saharan Africa

ALERT – Action Leveraging Evidence to reduce perinatal Mortality and morbidity in Sub-Saharan Africa

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
PACTR
Registry ID
PACTR202006793783148
Enrollment
144000
Registered
2020-06-17
Start date
2021-01-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth

Interventions

standard care

Sponsors

Karolinska Institutet
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: all women giving birth in selected hospitals (reproductive age) Their neonates (both sexes) after being born Hospitals selected based on the criteria: i) with an approximate minimum caseload of 3,000 deliveries per year ii) that offer caesarean section and blood transfusion services iii) that are preferably located in rural areas iv) present a mix of typical rural but also private-not-for-profit (faith-based) hospitals

Exclusion criteria

Exclusion criteria: Women in reproductive age admitted after giving birth

Design outcomes

Primary

MeasureTime frame
Fresh / intrapartum stillbirth rate defined as number of fresh stillbirths of at least 1000g expressed per 1,000 live and stillbirths;In-facility early perinatal mortality defined as number of fresh stillbirths (as above) and up-to discharge neonatal deaths per 1,000 live and stillbirths (composite indicator)

Secondary

MeasureTime frame
Hypoxic-ischaemic event rate;Neonatal seizures ;Caesarean section rate (%);Severe maternal morbidity;Responsiveness (%);Mistreatment (%)

Countries

Benin, Malawi, Tanzania, Uganda, United Republic of Tanzania

Contacts

Public ContactKristi Sidney Annerstedt

Postdoctoral researcher

kristi.sidney@ki.se+467079202081

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026