Nutritional, Metabolic, Endocrine
Conditions
Interventions
standard formula group
High protein formula group
Sponsors
Faculty of Medicine Tanta University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? Adult Brain Trauma patients of both sexes Glasgow Coma Scale = 8 and an injury severity score (ISS>15) who were admitted to our ICU within 24 hours after the injury. only well-nourished ( Modified Nutric –Score for Risk Screening = 0- 4) (10), previously healthy subjects will be recruited
Exclusion criteria
Exclusion criteria: ? Pregnancy, ? Vascular insufficiency or trauma to the lower limbs, ? History of neuromuscular diseases, ? Prolonged immobility prior to ICU admission, ? Comorbidities (renal, hepatic, cardiac disorders, chronic obstructive pulmonary disease, and diabetic patient), ? Patients with BMI = 35 , ? Patients with malignant diseases or immune disorders, ? Prolonged corticosteroids (CS) and/ or neuromuscular blocking agents (NMBA) use , ? ARDS patient (P/F ratio = 200), ? Sepsis, Multiorgan failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the percentage of reduction in the muscle mass measured by US. | — |
Secondary
| Measure | Time frame |
|---|---|
| -Pennation angle, cross sectional area, and Echogenicity of rectus femoris muscle, ;Length of mechanical ventilation and ICU stay | — |
Countries
Egypt
Contacts
Public ContactMona El Mourad
Lecturer
Outcome results
None listed