Perineural versus IV dexmedetomidine with adductor canal block for perioperative analgesia in total knee arthroplasty; a randomized prospective controlled study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202006770945823

Enrollment

100

Registered

2020-06-17

Start date

2019-09-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Group P addactor canal block ACB

group I ACB with the administration of dexmedetomidine

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) physical status I or II Patient scheduled for total knee arthroplasty

Exclusion criteria

Exclusion criteria: BMI > 35 kg/m2, pregnancy/lactation, any cardiac comorbidity, pre-existing neurological deficit, significant renal or hepatic impairment, severe pulmonary compromise, known contraindications to peripheral nerve block, allergies to local anaesthetic or dexmedetomidine, or chronic opioid users/abusers.

Design outcomes

Primary

Measure	Time frame
compare the duration of analgesia provided by ultrasound-guided adductor canal block (ACB) with either the addition of dexmedetomidine to the block or given intravenously (IV) intraoperatively in total knee replacement surgery.	—

Secondary

Measure	Time frame
Intraoperative and postoperative hemodynamics (MAP and HR), total analgesic (morphine) consumption, postoperative Ramsay sedation score, resting visual analogue scale (VAS), and dynamic VAS.	—

Countries

Egypt

Contacts

Public ContactAmin Ahmed

Professor Faculty of Medicine Alexandria University

aminrazek@yahoo.com0021227392464

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026