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PrEP Implementation of Mothers in Antenatal care

PrEP Implementation of Mothers in Antenatal care

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
PACTR
Registry ID
PACTR202006650810423
Enrollment
5000
Registered
2020-06-11
Start date
2017-09-04
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV/AIDS

Interventions

Universal arm
Targeted arm

Sponsors

National Institute of Health
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Age =15 years Pregnant at any gestational age Tuberculosis negative Plans to reside in area for at least one year postpartum Plans to receive postnatal and infant care at the study facility Not currently enrolled in any other studies.

Exclusion criteria

Exclusion criteria: HIV+ at time of enrollment

Design outcomes

Primary

MeasureTime frame
Maternal HIV Incidence

Secondary

MeasureTime frame
Appropriate PrEP Use. Scored 1 for high risk women using PrEP and low risk women not using PrEP; 0 for high risk women NOT on PrEP and low risk women using PrEP;PrEP Adherence and duration on PrEP through sequential dried blood spots and number of days on PrEP ;Infant birthweight, preterm birth, and growth curves. To compare infant outcomes in PrEP exposed infants vs. unexposed; ;To estimate the incremental cost-effectiveness of targeted PrEP compared to universal PrEP for women during pregnancy and in the postpartum period, per incident HIV infection and disability adjusted life year (DALY) averted.

Countries

Kenya

Contacts

Public ContactNancy Ngumbau

Study coordinator

nancym390@gmail.com254713917226

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026