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A randomised controlled trial comparing silver impregnated fibrous hydrocolloid dressings to silver sulfadiazine cream dressings for the treatment of fracture blisters to determine time to surgical readiness

A randomised controlled trial comparing silver impregnated fibrous hydrocolloid dressings to silver sulfadiazine cream dressings for the treatment of fracture blisters to determine time to surgical readiness

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202006616535482
Enrollment
128
Registered
2020-06-17
Start date
2018-07-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases Skin and Connective Tissue Diseases

Interventions

Silver sulfadiazine cream
Silver impregnated Fibrous Hydrocolloid Dressing

Sponsors

Tygerberg Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Fracture blisters overlying a fracture requiring surgical intervention 18 years of age or older

Exclusion criteria

Exclusion criteria: Fracture blisters overlying a fracture not requiring surgical intervention (conservatively managed) Patients younger than 18 years Patient refusal to participate Known povodine iodine allergy Known silver allergy Known sodium carboxymethylcellulose allergy

Design outcomes

Primary

MeasureTime frame
The aim of this study was to investigate, in patients suffering from fracture blisters, the time to surgical readiness in those treated with silver impregnated fibrous hydrocolloid dressings compared to those treated with topical silver sulfadiazine cream.

Secondary

MeasureTime frame
A secondary aim was to determine the direct costs associated with both treatments.

Countries

South Africa

Contacts

Public ContactMarilize Burger

Research coordinator

marilizecb@gmail.com0027820462614

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026