Musculoskeletal Diseases Nervous System Diseases
Conditions
Interventions
physical therapy
Sponsors
soher mohamed monuir hamza
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion Criteria: 1. Relapsing remitting MS recently diagnosed 2. Age range from 20-40 (P fleger CCH F. E.-H., 2010) 3. EDSS (Expanded Disability Status Scale) score less than 5 4. Vitamin D insufficiency less than 20- 30 ng/mL.
Exclusion criteria
Exclusion criteria: 1-Use of vitamin D supplements in the past 3 months. 2-Additional illness that would restrict their function, or suffered from a relapse within the last 4 months, as defined by Polman (Polman et al., 2011). 3-Relapse of disease and corticosteroids use in past month 4-Active inflammation at the start of the study (flu, cystitis etc.) 5-Renal disease 6-Elevated levels of calcium or parathyroid hormone 7-Switching of imunomodulatory drug in past 3 months 8-Hypersensitivity to vitamin D preparations 9-Cognitive impairment interfering with the subject’s ability to provide informed consent. 10-History of hyperparathyroidism, liver disease, tuberculosis, sarcoidosis and kidney stones (Lassmann, h 1999).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum vitamin D level | — |
Secondary
| Measure | Time frame |
|---|---|
| timed 25 walk test for lower limb functional improvement | — |
Countries
Egypt
Contacts
Public ContactAbeer abu bakr
profesor at faculty of physical therapy cairo university
Outcome results
None listed