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Effect of moringa oleifera leaves on the blood glucose, blood pressure, lipid profile and haematological parameters of type 2 diabetics in a rural Nigerian community.

Effect of moringa oleifera leaves on the blood glucose, blood pressure, lipid profile and haematological parameters of type 2 diabetics in a rural Nigerian community.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
PACTR
Registry ID
PACTR202005626842621
Enrollment
30
Registered
2020-05-04
Start date
2014-10-27
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nutritional, Metabolic, Endocrine

Interventions

Group 1
Group 2
Group 3

Sponsors

Ifeoma Christiana Afiaenyi
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Type 2 diabetics aged 40 years and above. Type 2 diabetics with no obvious complications such as foot ulcer, blindness and stroke. Type 2 diabetics who were neither pregnant nor breastfeeding. Type 2 diabetics who were not obese. Type 2 diabetics who consented to partake in the study.

Exclusion criteria

Exclusion criteria: Type 2 diabetics who were below 40 years of age. Type 2 diabetes with such complications such as foot ulcer, blindness and stroke. Type 2 diabetics who were either pregnant or breastfeeding. Type 2 diabetics who were obese. Type 2 diabetics who did not give their consent to partake in the study.

Design outcomes

Primary

MeasureTime frame
Lipid profile: There was a non-significant (p > 0.05) reduction in the mean total cholesterol level of the subjects in groups 1, 2 and 3. Group 2 and 4 had a non-significant (p > 0.05) increase in their mean serum triglyceride from 63.33 mg/dl to 109.00 mg/dl in group 2 and from 107.00 mg/dl to 112.5 mg/dl in group 4. There was a significant (p 0.05) reduction in the mean packed cell volume of the subjects in groups 1, 2 and 3 after the feeding trial. Only the group 4 subjects had a significant (p 0.05) decrease in the mean fasting blood glucose levels of the subjects in group 1 (from 163.67 mg/dl before the feeding to 161.17 mg/dl after the feeding trial). Subjects in group 2 had a non-significant (p > 0.05) increase in their fasting blood glucose level from 146.00 mg/dl before the feeding to 158.00 mg/dl after the feeding. There was a reduction in the fasting blood glucose level of the subjects in group 3 (from 228.33 mg/dl to 225.00 mg/dl); however, the decrease was not significant (p > 0.05). Subjects in group 4 had a non-significant (p > 0.05) increase in their fasting blood glucose levels from 244.00 mg/dl to 265.17 mg/dl before and after the feeding trial respectively.;Blood pressure. Group 3 subjects had a significant (p 0.05) reduction in the diastolic blood pressure of the subjects in groups 2, 3 and 4 from 76.33 mmHg, 78.33 mmHg and 84.00 mmHg before the feeding trial to 71.33 mmHg, 72.00 mmHg and 77.00 mmHg after the feeding trial respectively.

Secondary

MeasureTime frame
Anthropometric measurements. There was a significant (p 0.05) decrease in their mean BMI from 24.45 kg/m2 before the feeding to 24.08 kg/m2 after the feeding. There was a non-significant (p > 0.05) decrease in the mean waist circumference of subjects in groups 2 and 3 from 87.50 cm and 92.17 cm before the feeding to 87.33 cm and 91.17 cm after the feeding trial respectively. Groups 2, 3 and 4 had a non-significant (p > 0.05) decrease in their mean waist hip ratio from 1.02 to 1.01, 1.01 to 1.00 and 1.03 to 1.02 before and after the feeding trial respectively.

Countries

Nigeria

Contacts

Public ContactElizabeth Ngwu

Professor. Universoty of Nigeria Nsukka.

elizabeth.ngwu@unn.edu.ng+23408039223452

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026