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Analgesic effect of Transcutaneous Electrical Nerve Stimulation on patients with chronic back pain

Serial correlation of temporal pain intensities with beta-endorphin and meta-enkephalin concentrations, following Transcutaneous Electrical Nerve Stimulation among patients with chronic low back pain: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202004888024754
Enrollment
70
Registered
2020-04-22
Start date
2012-11-06
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases

Interventions

Sponsors

Charles Ikechukwu Ezema
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ambulatory male or female patients aged 20–70 years who had been clinically diagnosed of CLBP resulting from lumbar spondylosis of not less than six months duration with pain intensity NRS = 5 who were referred for physiotherapy,

Exclusion criteria

Exclusion criteria: previous use of therapeutic electrical stimulation modality pregnancy diabetes prior lumbar spine surgery history of cancer, cardiovascular, gynaecological, urological, and neurologic conditions severe spinal orthopaedic conditions such as pott’s disease, disc protrusion, lumbar (spinal and foramina) stenosis, radiculopathy, and spondylolisthesis > 1 cm skin lesions between L1 to L5 pain on vertical oscillatory thrust of any spinal vertebrae beyond L1 to L5 pain from hips and sacroiliac joints implanted electronic device (pacemaker) use of steroids and central nervous system stimulants

Design outcomes

Primary

MeasureTime frame
Pain intensity of Numeric Rating Scale

Secondary

MeasureTime frame
plasma concentrations of beta-endorphin and met-enkephalin

Countries

Nigeria

Contacts

Public ContactOgochukwu Onyeso

Research Associate Department of Medical Rehabilitation University of Nigeria

kzetfrank@yahoo.com+2348060905846

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026