Genicular nerve blockade for the treatment of chronic knee pain: a clinical study comparing the classical versus revised anatomical targets

A comparison of genicular nerve blockade using classical versus revised anatomical landmarks for painful knee osteoarthritis: a double-blind, randomized clinical study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202004822698484

Enrollment

Registered

2020-04-02

Start date

2019-06-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthopaedics Anaesthesia

Interventions

Genicular nerve Blockade using revised landmarks

Genicular nerve Blockade using classical landmarks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Chronic knee pain (Numeric rating scale (NRS) >5/10, for more than three months); radiological tibio-femoral confirmation of knee osteoarthritis (Kellgren-Lawrence grade 2–4); and pain was not relieved by conservative treatment (oral medication, intra-articular injections with corticoids and viscosupplementation).

Exclusion criteria

Exclusion criteria: Connective tissue diseases that affected the knee; skin lesion on the knee; steroid or hyaluronic acid injection therapy during the previous 3 months; knee surgery scheduled in the next three months; anticoagulant medication use; unbalanced diabetes mellitus or hypertension; patients unable to walk.

Design outcomes

Primary

Measure	Time frame
Change in NRS score from baseline knee pain to 3 months after the treatment	—

Secondary

Measure	Time frame
- The proportion of subjects whose knee pain was reduced by 50% or greater from baseline at 3 months after treatment. - Change in knee function detected by OKS and WOMAC - Objective change in the locomotion as reflected by the walking speed on a 10 meter-track and the walking endurance assessed during a 6 minute free walking test - Analgesic use, as measured by subject self-reported quantitative analgesic questionnaire	—

Measure

Time frame

- The proportion of subjects whose knee pain was reduced by 50% or greater from baseline at 3 months after treatment. - Change in knee function detected by OKS and WOMAC - Objective change in the locomotion as reflected by the walking speed on a 10 meter-track and the walking endurance assessed during a 6 minute free walking test - Analgesic use, as measured by subject self-reported quantitative analgesic questionnaire

—

Countries

Cameroon

Contacts

Public ContactHerman;Loic Fossoh;Fonkoue

Centre Hospitalier Dominicain saint Martin de Porres;University of Yaounde 1

hffossoh@yahoo.fr;fonkoueloic@yahoo.fr+237696393762;+237699666757

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026