Skin and Connective Tissue Diseases
Conditions
Interventions
Fractional microneedle radiofrequency
Sponsors
Faculty of Medicine Cairo University Kasr AlAiny
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • Patients with post burn hypertrophic scars more than one year. • Participants should be more than 16 years old. • Both males and females • Patents with two separate lesions, each of them about 2 to 3 cm OR a single large sized lesion equal to or more than 10 cm.
Exclusion criteria
Exclusion criteria: • Patients with unrealistic expectations. • Patients with active skin, infections e.g herpes or autoimmune disease. • Non compliant patient. • Patients who had received any form of treatment during the last eight weeks prior to treatment (such as intralesional steroid injection) or a laser procedure during the last six months. • Recent use of isotretinoin within six months prior to the procedures. • Patient with known allergy to lidocaine. • Pregnancy, Lactation. • Patients with previous history of adverse outcome related to laser.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| To compare the fractional Co2laser versus fractional microneedle radiofrequency in the treatment of post burn scars clinically, histopathologically and biochemically. | — |
Primary
| Measure | Time frame |
|---|---|
| 1-To assess the improvement in the selected treated burn scars by fractional Co2laser and fractional microneedle radiofrequency. 2-To assess the improvement in the density and arrangement of collagen fibers and elastic fibershistopathologically. 3-To assess the tissue level of TGFß1before and after both treatment modalities. | — |
Countries
Egypt
Contacts
Public ContactFatma El Zahraa Hamouda
Specialist of dermatology in Gharb Aswan Hospital
Outcome results
None listed