Comparison of the Effect of Prophylactic Intravenous Tranexamic Acid to Infusion Oxytocin as Adjuncts to Bolus Oxytocin on Blood Loss at Caesarean Section. A Randomised Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202004798040817

Enrollment

144

Registered

2020-04-24

Start date

2019-01-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fertility-female

Interventions

Intravenous Tranexamic Acid

Oxytoxin infusion

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women with singleton pregnancy at gestational age >37 weeks

Exclusion criteria

Exclusion criteria: Non consenting women Multiple gestation Pregnancy with co-existing uterine fibroid Hypertensive disorders Anaemia (Hb<10g/dl) Heart disease Renal disease Liver disease Placenta praevia Abruption placenta Previous history of thromboembolism. Allergy to oxytocin or tranexamic acid.

Design outcomes

Primary

Measure	Time frame
Difference in mean blood loss between both arms of the study	—

Secondary

Measure	Time frame
- Incidence of postpartum haemorrhage in both arms of the study. - Incidences of greater than 10% fall in haemoglobin concentration in both arms of the study. - Proportion of women in both arms who require medical and surgical interventions. - Proportion of women who need blood transfusion in both arms of the study. - The proportion of women with haemodynamic instability and adverse drug effects.	—

Countries

Nigeria

Contacts

Public ContactOguntayo AO

Secondary Researcher

fayokunmi@yahoo.co.uk+2348033109752

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026