COVID-19
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients with confirmed clinical and laboratory diagnosis of COVID-19. Patients with normal liver and renal function markers.
Exclusion criteria
Exclusion criteria: Pregnant, lactating and breastfeeding women. Patients with diabetes or with serious ailments of heart, liver, kidney or brain. Chronic medical disorders including HIV/AIDS, Cancers, etc. Subjects who have any allergy or were allergic to any of the medication to be used.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The mean time to negative test to COVID-19.;Presence of immune determinants. | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of patients with persisting respiratory symptoms (cough, expectoration, nasal discharge, headache, fever, sore throat, earache, malaise/fatigue and sleep disturbance) ;Incidence of any adverse events (such as diarrhea, nausea, vomiting and colitis) ;Mean levels of renal function parameters (serum electrolyte, urea and creatinine). ;Mean levels of liver function parameters (AST, ALT and ALP) and lipid profiles.;Proportion of patients discharged from hospital or deaths;Effects (if any) on CD4+ and CD8+ counts of both Study Arms | — |
Countries
Nigeria
Contacts
Consultant