Effects of walnut consumption associated with physical activities on biological responses and physical performances in elderly men.

Effects of walnut supplementation associated with concurrent training on biological responses, postural control and isokinetic knee strength in aging men.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

PACTR

Registry ID

PACTR202004543859924

Enrollment

Registered

2020-04-14

Start date

2017-01-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aging men

Interventions

Walnut consumption and Training

Training

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: - Physically active elderly male (=65 years). - No smoking or alcoholic - Healthy men - Active men

Exclusion criteria

Exclusion criteria: - Participants with a background in systematic physical training during the 2 months before the study were excluded. - Renal, endocrine, gastrointestinal pathology - Walnut allergy, - Pathological ECG.

Design outcomes

Primary

Measure	Time frame
1-Change in physical performance in both group (Experimental, E and Conctol C). The Isokinetic knee strength was measured with a Cybex® Norm II Medimex. The peak torque of knee extensor and flexor was assessed with five repetitions at speed of 120°.s-1. 2-Change in postural parameters only for E group. Bipedal with duel-task (counting from 0 to add 7 each time) balance measurements were performed in both conditions “open eyes” (OE) and “closed eyes” (CE) using the SATEL® force platform. 3-Change in lipid profile compared to baseline for E but not for C group. Lipid profile (i.e. Total Cholesterol (TC), Total, High-density lipoprotein (HDL), Low-density lipoprotein (LDL) and Triglycerides (TG)) were measured enzymatically. 4-Change in systematic inflammation compared from baseline for E but not for C group. CRP was measured with the immune-turbidimetric method. 5-Change in steroid hormones compared from baseline for E but not for C group. Testosterone (T) and Cortisol (C) concentrations were assessed by chemiluminescent micro-particle immunoassay (CMIA). 6-Change is muscular damage compared from baseline for E but not for C group. Creatine Kinase (CK), Lactate Deshydrogenase (LDH) concentrations were respectively measured with N-acetyl-L-cysteine method; the oxidation of lactate on pyruvate method.	—

Measure

Time frame

1-Change in physical performance in both group (Experimental, E and Conctol C). The Isokinetic knee strength was measured with a Cybex® Norm II Medimex. The peak torque of knee extensor and flexor was assessed with five repetitions at speed of 120°.s-1. 2-Change in postural parameters only for E group. Bipedal with duel-task (counting from 0 to add 7 each time) balance measurements were performed in both conditions “open eyes” (OE) and “closed eyes” (CE) using the SATEL® force platform. 3-Change in lipid profile compared to baseline for E but not for C group. Lipid profile (i.e. Total Cholesterol (TC), Total, High-density lipoprotein (HDL), Low-density lipoprotein (LDL) and Triglycerides (TG)) were measured enzymatically. 4-Change in systematic inflammation compared from baseline for E but not for C group. CRP was measured with the immune-turbidimetric method. 5-Change in steroid hormones compared from baseline for E but not for C group. Testosterone (T) and Cortisol (C) concentrations were assessed by chemiluminescent micro-particle immunoassay (CMIA). 6-Change is muscular damage compared from baseline for E but not for C group. Creatine Kinase (CK), Lactate Deshydrogenase (LDH) concentrations were respectively measured with N-acetyl-L-cysteine method; the oxidation of lactate on pyruvate method.

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Secondary

Measure	Time frame
1- Change is sleep quality for Experimental and Control group compared to baseline. The Spiegel sleep questionnaire includes six questions to judge the quality of sleep. It calculates a score that ranges from 0 to 30. The higher is the score, the better is the sleep quality. 2- Change in cognitive performances for Experimental compared to C group. The Montreal Cognitive Assessment (MoCA) was designed as a rapid screening instrument for evaluation of cognitive performances. It assesses different cognitive domains: attention and concentration, executive functions, memory, language, Visio-constructional skills, conceptual thinking, calculations and orientation. 3- Change is oxidative parameters compared to baseline for Experiental and not for Control group. MDA, GSH, THT and AOPP were measured by manual protocol.	—

Measure

Time frame

1- Change is sleep quality for Experimental and Control group compared to baseline. The Spiegel sleep questionnaire includes six questions to judge the quality of sleep. It calculates a score that ranges from 0 to 30. The higher is the score, the better is the sleep quality. 2- Change in cognitive performances for Experimental compared to C group. The Montreal Cognitive Assessment (MoCA) was designed as a rapid screening instrument for evaluation of cognitive performances. It assesses different cognitive domains: attention and concentration, executive functions, memory, language, Visio-constructional skills, conceptual thinking, calculations and orientation. 3- Change is oxidative parameters compared to baseline for Experiental and not for Control group. MDA, GSH, THT and AOPP were measured by manual protocol.

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Countries

Tunisia

Contacts

Public ContactOmar Hammouda

2 The Research Unit of the assessment of musculoskeletal disorders

hammouda.o@parisnanterre.fr+21652785747

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026