Skip to content

Comparison between two low doses of Amitriptyline in the management of chronic neck pain. A Randomized double-blind comparative study.

Comparison between two low doses of Amitriptyline in the management of chronic neck pain. A Randomized double-blind comparative study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202003721200086
Enrollment
150
Registered
2020-03-26
Start date
2019-05-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases Nervous System Diseases Orthopaedics

Interventions

5 mg of amitriptyline.
10 mg Amitriptyline dose

Sponsors

Fayoum University Hospitals
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Presence of CNP for more than 15 days/month during at least three consecutive months. 2. Patients without previous trauma. 3. Patients free from other neurologic disorders except for chronic tension headaches. 4. Age from18 to 75 years. 5. Normal neurologic examination (performed by a neurologist) except for pericranial tenderness. 6. No imaging abnormalities except for a loss of cervical lordosis.

Exclusion criteria

Exclusion criteria: 1. The presence of neurologic disorder revealed an abnormal clinical examination. 2. Abnormal imaging or history of cervical disc disease. 3. Migraine headache. 4. History of trauma. 5. Major depressive disorder. 6. Analgesic abuse. 7. History of intolerance to tricyclic or tetracyclic antidepressants. 8. Current psychiatric disorder. 9. Glaucoma, cardiac rhythm abnormalities, severe constipation. 10. Patients on medications for CNP other than NSAID or paracetamol taken during the last month. 11. Pregnancy in women and prostatic symptoms in men.

Design outcomes

Primary

MeasureTime frame
Neck Pain Disability Index. NPDI

Secondary

MeasureTime frame
Neck pain intensity;Athens Insomnia Scale;Anxiety and depressive symptoms will be evaluated with Hospital Anxiety and Depression Scale (HADS),

Countries

Egypt

Contacts

Public ContactAtef Khaleel.

Lecturer of Anesthesiology Fayoum University

mygodprotection@yahoo.com00842114059

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026