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Efficacy and safety of Glucosamine sulfate and chondroitin sulfate combination in the treatment of haemophilic arthropathy: randomized, double-blind, placebo-controlled trial

Efficacy and safety of Glucosamine sulfate and chondroitin sulfate combination in the treatment of haemophilic arthropathy: randomized, double-blind, placebo-controlled trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
PACTR
Registry ID
PACTR202002466895205
Enrollment
45
Registered
2020-02-20
Start date
2020-03-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthopaedics

Interventions

Glucosamine sulphate and chondroitin sulphate combination
Placebo

Sponsors

Faculty of pharmacy university of khartoum
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: • patients diagnosed as having haemophilia A or B, • patients at least 5 years old at the time of enrollment, • patients classified as having haemophilc arthropathy in Arnold-Hilgartner scale, • no concurrent medical or arthritic conditions that could confound evaluation of the index joint, • No other active or severe diseases.

Exclusion criteria

Exclusion criteria: • Patients with bleeding disorders other than haemophilia A and B, • Patients less than 5 years old, • Patients with severe haemophilic arthropathy classified as class O, or IV in Arnold-Hilgartner scale of haemophilic arthropathy, • Patients with positive results in HIV, HB, or HC screening tests. • a history of clinically significant trauma or surgery to the joints, • Or coexisting disease that could preclude successful completion of the trial.

Design outcomes

Primary

MeasureTime frame
Improvement of participant sore in the clinical evaluation of haemophilic arthropathy scale.;Improvement of participant score in radiological evaluation using Arnold-Hilgartner scale of haemophilic arthropathy.

Secondary

MeasureTime frame
Quality of life

Countries

Sudan

Contacts

Public ContactAhmed Mudawi Musa

Profeesor at institute of endemic diseases university of Khartoum

musaam2003@yahoo.co.uk00249918043288

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026