Oral Health
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Male or female Patients with age ranging from 18 to 50 years old. 2) Patients complaining from intermittent or spontaneous, sharp or dull, localized, diffuse, or referred pain. 3) Patients’ selected teeth presented with fully developed roots. 4) Selected teeth should give positive responses to cold testing. 5) Selected teeth eliciting prolonged episodes of pain on rapid exposure to dramatic temperature changes and lasting even after the thermal stimulus had been removed. 6) Periapical radiographs showed deep carious lesions. 7) Soft tissues around the tooth were normal. 8) The patients were free from any coagulation disorders, with normal platelets count.
Exclusion criteria
Exclusion criteria: 1) Badly broken or non-restorable teeth. 2) Patients with multiple teeth seeking root canal treatment in the same side. 3) Teeth with Pathological mobility. 4) Pus discharge through an associated sinus tract. 5) Radiographic internal or external resorption or furcation radiolucency. 6) Medically compromised patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aim of the present study is to assess the clinical and radiographic success rate of the regenerative pulpotomy procedure done in irreversibly inflamed permanent mature teeth using: a) Biodentine. b) Mineral trioxide aggregate (MTA). c) Platelet rich fibrin (PRF) and Biodentine. d) Platelet rich fibrin and Mineral trioxide aggregate. | — |
Secondary
| Measure | Time frame |
|---|---|
| CBCT analysis is done immediate post-operative and at the end of the follow up period ;is to evaluate the ability of PRF membrane to regenerate the coronal pulp and maintaining the tooth vitality using pulse oximetry. | — |
Countries
Egypt
Contacts
Professor of Endodontics Faculty of Dentistry Alexandria University;Professor of Endodontics Faculty of Dentistry Alexandria university