Cancer
Conditions
Sponsors
National cancer institute
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • Greater than or equal to 18 years of age. • Clinical performance status of ECOG = 2. • Stable serum CEA levels not indicating recurrence. • No history of prior/other malignancies within the 2 years prior to enrollment with the exception of basal cell carcinoma.
Exclusion criteria
Exclusion criteria: • Active systemic infections, coagulation disorders, or other major medical illnesses precluding major surgery. • Prior experimental therapy with novel agents. • Prior HIPEC. • History of brain metastases. • Childs B or C cirrhosis or with evidence of severe portal hypertension by history, endoscopy, or radiologic studies or with evidence of moderate to severe ascites. • Weight less than 40 kg. • History of congestive heart failure and/or an LVEF < 40%. • Significant COPD or other chronic pulmonary restrictive disease with PFT's indicating an FEV1 less than 50% or a DLCO less than 40% predicted for age.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| judge the efficacy of the early use of steroid therapy in reducing chemotherapy induced myocarditis following cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy in the early post-operative period. | — |
Secondary
| Measure | Time frame |
|---|---|
| echocardiographic assessment of left ventricular ejection fraction (LVEF) and fractional shortening (LVFS) for all patients. | — |
Countries
Egypt
Contacts
Public ContactIhab saad
national cancer institute
Outcome results
None listed